Aamir Khan: Live | Exclusive: Mumbai set for 'Indian Aamir Khan Live' at JIO
In Mumbai, JIO(Jio Institute of Openness) and NDTV with Bollywood superstarAamir Khan will showcase the largest free open air live conversation on JIO in history.Mr. Aamir Khan will be revealing the ‘India Live’ on June 19 on NDTV. The live conversation will be a bit different from the usual ones, as Mr. Khan will be answering the questions live. You can join the conversation by tweeting with the hashtag #INDIALIVE. The JIO Live will be broadcast live on NDTV and JIO’s official channels. The broadcast will be available in English and Marathi.
This live conversation was held at JIO’s Vigyan Bhavan in Mumbai on June 15, 2017. The live interaction saw more than 150 academics from various fields (including the fields of journalism, science, business, social sciences, engineering, law etc.) asking more than 200 questions.Regulation of basic fibroblast growth factor expression in a human osteosarcoma cell line by dexamethasone.
Basic fibroblast growth factor (bFGF) is expressed in a variety of normal and neoplastic tissues and may have a role in the early phases of tumor growth. To determine whether this growth factor is involved in the regulation of bone resorption, we have investigated the effect of dexamethasone (Dex) on the production and expression of bFGF in a human osteosarcoma cell line, UMR 106-01. In this report, we show that Dex induces the production and expression of bFGF mRNA in a dose-dependent manner. Dex concentrations of 1 microM or greater inhibit both bFGF production and expression. Dex-induced inhibition is maximal after 48-96 h of treatment, during which time cell proliferation is also maximally inhibited. Inhibition of bFGF production and expression by Dex is not associated with increased cell death and is not mediated by the classical glucocorticoid receptor. These results suggest that the induction of bFGF by Dex is a separate glucocorticoid-independent pathway which may play an important role in the mechanisms of action of Dex.Blog
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